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Best aspirins - April 2026

Last Updated - April 1, 2026

1
Best Choice

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Bayer

Bayer Genuine Aspirin 325 mg, Coated Tablets for Headache Relief, Multi-Symptom Pain Reliever and Fever Reducer, Pain Relief Tablets for Tooth and Muscle Pain, Backache, 300 Ct

Bayer

$16.46

More Details
Main highlights
- Over 125 Years of Pain Relief: Bayer has been providing safe, effective pain relief for over a century when used as directed.
- Multi-Symptom Pain Reliever and Fever Reducer: Relieves tooth pain, backache, muscle aches, menstrual pain, and minor arthritis pain, and also reduces fever
- Helps Prevent Another Heart Attack or Ischemic Stroke: When directed by a doctor, Bayer Aspirin can help prevent another heart attack or clot-related (ischemic) stroke. Aspirin is not appropriate for everyone, so be sure to talk to your doctor before you begin an aspirin regimen.
- Headache Relief: Provides proven headache relief so you can get back to your day with confidence
- Easy to Swallow: Each pain relief tablet is coated for easy swallowing and is free of caffeine and sodium
- 325 Mg Per Tablet: Each coated tablet of Genuine Bayer Aspirin contains 325 mg of aspirin (NSAID)* for effective headache and multi-symptom pain relief
$16.46
2

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Bayer

Bayer Genuine Aspirin 325 mg, Coated Tablets for Headache Relief, Multi-Symptom Pain Reliever and Fever Reducer, Pain Relief Tablets for Tooth and Muscle Pain, Backache, 300 Ct

Bayer

$15.64

$16.46
(5% Off)

More Details
Main highlights
- Over 125 Years of Pain Relief: Bayer has been providing safe, effective pain relief for over a century when used as directed.
- Multi-Symptom Pain Reliever and Fever Reducer: Relieves tooth pain, backache, muscle aches, menstrual pain, and minor arthritis pain, and also reduces fever
- Helps Prevent Another Heart Attack or Ischemic Stroke: When directed by a doctor, Bayer Aspirin can help prevent another heart attack or clot-related (ischemic) stroke. Aspirin is not appropriate for everyone, so be sure to talk to your doctor before you begin an aspirin regimen.
- Headache Relief: Provides proven headache relief so you can get back to your day with confidence
- Easy to Swallow: Each pain relief tablet is coated for easy swallowing and is free of caffeine and sodium
- 325 Mg Per Tablet: Each coated tablet of Genuine Bayer Aspirin contains 325 mg of aspirin (NSAID)* for effective headache and multi-symptom pain relief
$15.64
$16.46 (5% Off)
3

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Bayer

Bayer Aspirin Low Dose 81 mg, Enteric Coated Tablets, Doctor Recommended, Secondary Prevention of Cardiovascular Disease, 300 Safety Coated Tablets (Packaging may vary)

Bayer

$14.97

More Details
Main highlights
- Multi-Symptom Pain Reliever and Fever Reducer: Genuine Bayer Aspirin provides proven relief of headache, backache, muscle pain, toothache, menstrual pain, as well as minor arthritis pain relief, and reduces fever
- Helps Prevent Another Heart Attack or Ischemic Stroke: Genuine Bayer Aspirin can help prevent another heart attack or clot-related (ischemic) stroke
- Free From: Each pain medicine tablet is free of caffeine and sodium and is coated to make it easier for swallowing
- Aspirin is not appropriate for everyone, so be sure to talk to your doctor before you begin an aspirin regimen
- 325 Mg Per Tablet: Each coated tablet of Genuine Bayer Aspirin contains 325 mg of the active ingredient aspirin (NSAID)*
- 125 Years of Relief: Bayer Aspirin has been a leading aspirin brand in pain relief
$14.97
4

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Bayer

Bayer Aspirin Low Dose 81 mg, Enteric Coated Tablets, Doctor Recommended, Secondary Prevention of Cardiovascular Disease, 300 Safety Coated Tablets (Packaging may vary)

Bayer

$14.22

$14.97
(5% Off)

More Details
Main highlights
- Multi-Symptom Pain Reliever and Fever Reducer: Genuine Bayer Aspirin provides proven relief of headache, backache, muscle pain, toothache, menstrual pain, as well as minor arthritis pain relief, and reduces fever
- Helps Prevent Another Heart Attack or Ischemic Stroke: Genuine Bayer Aspirin can help prevent another heart attack or clot-related (ischemic) stroke
- Free From: Each pain medicine tablet is free of caffeine and sodium and is coated to make it easier for swallowing
- Aspirin is not appropriate for everyone, so be sure to talk to your doctor before you begin an aspirin regimen
- 325 Mg Per Tablet: Each coated tablet of Genuine Bayer Aspirin contains 325 mg of the active ingredient aspirin (NSAID)*
- 125 Years of Relief: Bayer Aspirin has been a leading aspirin brand in pain relief
$14.22
$14.97 (5% Off)
5
Best Value
13% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

PHARBEST
13% Off

PHARBEST Aspirin 325 mg | Regular Strength | 1000 Count Uncoated Tablets

PHARBEST

$12.99

$14.85
(13% Off)

More Details
Main highlights
- Relief from Pain and Fever: Like Bayer Aspirin, it is designed to provide relief from pain and reduce fever, making it suitable for various conditions.
- Manufactured in the USA: Both products are manufactured in the USA, meeting quality standards and assuring consumers of their reliability and safety.
- Generous Supply: With 1000 uncoated tablets per supply, it ensures long-lasting relief for individuals seeking pain relief over an extended period.
- Cost-Effective Alternative: While Genuine Bayer Aspirin may carry brand name recognition, the comparison product offers a cost-effective alternative with identical active ingredients and efficacy.
- Comparable Formulation: The product being compared to Genuine Bayer Aspirin contains Regular Strength Aspirin at 325 mg per tablet, offering a comparable formulation for pain relief and fever reduction.
$12.99
$14.85 (13% Off)

Best aspirins - April 2026

Bayer Genuine Aspirin 325 mg, Coated Tablets for Headache Relief, Multi-Symptom Pain Reliever and Fever Reducer, Pain Relief Tablets for Tooth and Muscle Pain, Backache, 300 Ct

Bayer Genuine Aspirin 325 mg, Coated Tablets for Headache Relief, Multi-Symptom Pain Reliever and Fever Reducer, Pain Relief Tablets for Tooth and Muscle Pain, Backache, 300 Ct

Bayer Aspirin Low Dose 81 mg, Enteric Coated Tablets, Doctor Recommended, Secondary Prevention of Cardiovascular Disease, 300 Safety Coated Tablets (Packaging may vary)

Bayer Aspirin Low Dose 81 mg, Enteric Coated Tablets, Doctor Recommended, Secondary Prevention of Cardiovascular Disease, 300 Safety Coated Tablets (Packaging may vary)

PHARBEST Aspirin 325 mg | Regular Strength | 1000 Count Uncoated Tablets

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PHARBEST Aspirin 325 mg | Regular Strength | 1000 Count Uncoated Tablets

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Amazon Basic Care Aspirin 81 mg Pain Reliever (NSAID) Chewable Tablets, Low Dose , Orange Flavor, 36 Count (Pack of 3)

Amazon Basic Care Aspirin 81 mg Pain Reliever (NSAID) Chewable Tablets, Low Dose , Orange Flavor, 36 Count (Pack of 3)

Amazon Basic Care Low Dose Aspirin 81 mg Chewable Tablets, Pain Reliever for Minor Aches, Orange Flavor, 36 Count

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