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Best medicines - October 2025

Last Updated - October 4, 2025

1
Best Choice
20% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Boiron
20% Off

Boiron Oscillococcinum for Relief from Flu-Like Symptoms of Body Aches, Headache, Fever, Chills, and Fatigue - 30 Doses

Picked by 393 people in the last week

Boiron

$26.99

$33.99
(20% Off)

More Details
Main highlights
- THE BOIRON PROMISE: We believe there’s a better way to feel better. Since 1932, we’ve been dedicated to providing the purest medicines made from earth’s best resources
- SHORTEN YOUR SYMPTOMS: Oscillo has been shown in clinical studies to help reduce both the duration and the severity of flu-like symptoms when taken at the onset.* Non-drowsy, easy-to-take relief
- HSA & FSA eligible: Oscillococcinum is HSA & FSA eligible
- HOMEOPATHIC FLU RELIEF: Oscillococcinum works with your body to help relieve body aches, headache, fever, chills, and fatigue.* Ideal for ages 2 and up, take at the first sign of flu-like symptoms
- HOLISTIC SUPPORT: Looking for homeopathic flu relief for the whole family? Oscillococcinum’s meltaway pellets dissolve easily in the mouth; no water, chewing, or swallowing required
- A BETTER WAY TO FEEL BETTER: Homeopathic medicines use highly diluted botanical, biological, or mineral substances to relieve symptoms. They work with your body without the risk of known drug interactions
$26.99
$33.99 (20% Off)
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Vicks

VICKS DayQuil & NyQuil SEVERE Honey Flavor Co-Pack, Cold & Flu Medicine, Relieves Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, and Cough, 2x12oz

Vicks

$19.97

More Details
Main highlights
- WORLD'S TOP SELLING OTC COUGH AND COLD BRAND: Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms
- PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS: Life doesn't stop when you have a cold; NyQuil and DayQuil SEVERE Honey tackle your most bothersome cold & flu symptoms
- POWERFUL, MAXIMUM STRENGTH 9-SYMPTOM RELIEF DAY AND NIGHT: Use non-drowsy DayQuil SEVERE Honey for daytime and at night try NyQuil SEVERE Honey for fast relief so you can rest
- POWERFUL COLD & FLU RELIEF: DayQuil and NyQuil SEVERE Honey formulas are flavored with real honey & temporarily relieve common cold & flu symptoms
- GREAT-TASTING HONEY FLAVORED DAYQUIL AND NYQUIL: Get the same cold & flu relief you expect from DayQuil & NyQuil SEVERE in a great-tasting honey-licious flavor
$19.97
3
Best Value
24% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Tylenol
24% Off

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes for Fast Release, Gentle on Stomach, 500 mg Per Gelcap, 100 Count OTC Medicine

Tylenol

$12.47

$16.59
(24% Off)

More Details
Main highlights
- Rapid-release technology: Laser-drilled holes in each gelcap release acetaminophen faster for extra strength pain relief; gelcaps are gentle on the stomach and suitable for adults and children 12 years and older
- Multi-symptom support: Use as a fever reducer and to relieve headache, backache, muscle aches, arthritis pain, toothache, and joint discomfort; also helps with menstrual and premenstrual cramps and pain from the common cold or flu
- Fast-acting relief: Tylenol Extra Strength Rapid Release Gels feature 500 mg acetaminophen per gelcap to temporarily relieve minor aches and pains from headache, backache, arthritis, toothache, menstrual cramps, muscle aches, and fever; 100-count
- Dosage instructions: Adults and children 12 years and older take two gelcaps every six hours while symptoms last; do not exceed six gelcaps in 24 hours; always follow the label directions for safe use of acetaminophen and dosing guidance
- Doctor-recommended brand: Choose Tylenol, the #1 doctor-recommended brand for pain relief and fever reduction based on 2021 IQVIA survey; over-the-counter medication with 500 mg acetaminophen per gelcap that’s gentle on the stomach
$12.47
$16.59 (24% Off)
4

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Vicks

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

Vicks

$19.28

More Details
Main highlights
- WORLD'S #1 SELLING OTC COUGH AND COLD BRAND. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms.
- RELIEF YOU TRUST, DAY & NIGHT. Use non-drowsy DayQuil SEVERE for daytime relief and at night try NyQuil SEVERE for fast relief so you can rest.
- PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil and DayQuil SEVERE tackle your most bothersome cold & flu symptom
- POWERFUL COLD & FLU RELIEF. DayQuil and NyQuil SEVERE temporarily relieve common cold & flu symptoms
- NOTHING WORKS FASTER. Just one dose starts working fast to provide effective cold & flu relief
$19.28
5

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Amazon Basic Care

Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1) (Packaging may vary)

Amazon Basic Care

$9.39

More Details
Main highlights
- TREATS FREQUENT HEARTBURN: Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg treat frequent heartburn that occurs 2 or more times a week
- Product may be manufactured in India or Israel
- HEARTBURN TIPS: Do not eat late at night or just before bedtime. Certain foods or drinks are more likely to cause heartburn, such as rich, spicy, fatty and fried foods, chocolate, caffeine, alcohol and even some fruits and vegetables.
- ACTIVE INGREDIENT: The active ingredient in these delayed release tablets is omeprazole 20 mg, which works as an acid reducer to treat frequent heartburn. Compare to Prilosec OTC
- ACID REDUCER: Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg is a Proton Pump Inhibitor (PPI) that deactivates pumps in the stomach lining to inhibit acid production at the source.
- 14-DAY COURSE OF HEARTBURN TREATMENT: Taken once every 24 hours for 14 days, Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg is not intended for immediate relief of heartburn and may take 1 to 4 days for full effect.
$9.39

Best medicines - October 2025

Boiron Oscillococcinum for Relief from Flu-Like Symptoms of Body Aches, Headache, Fever, Chills, and Fatigue - 30 Doses

VICKS DayQuil & NyQuil SEVERE Honey Flavor Co-Pack, Cold & Flu Medicine, Relieves Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, and Cough, 2x12oz

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes for Fast Release, Gentle on Stomach, 500 mg Per Gelcap, 100 Count OTC Medicine

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1) (Packaging may vary)

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Amazon Basic Care Ibuprofen Tablets 200 mg, Pain Reliever/Fever Reducer, Body Aches, Headache, Arthritis Pain Relief and More, 500 Count (Packaging may vary)

Mucinex Rapid Clear Maximum Strength Cold Medicine & Expectorant, Fever, Pain, Headache, & Excess Mucus Relief with Acetaminophen & Guaifenesin, Rapid Release Caplets for Adults, 20 Count

Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)

Sudafed PE Sinus Pressure + Pain Relief Tablets, Maximum Strength, Non-Drowsy, OTC Sinus Relief Medicine with Acetaminophen Pain Reliever & Phenylephrine HCl Nasal Decongestant, 24 ct

Vicks VapoRub, Lavender Scent, Cough Suppressant, Topical Chest Rub & Analgesic Ointment, Medicated Vicks Vapors, Relief from Cough Due to Cold, Aches & Pains, 1.76oz

Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.

Neosporin Original First Aid Antibiotic Ointment with Bacitracin Zinc for Infection Protection, Wound Care Treatment & Scar Appearance Minimizer for Minor Cuts, Scrapes and Burns,.5 oz

Midol Complete Menstrual Pain Relief Caplets, 40 Count - Provides Cramp, Headache, and Bloating Relief

Mucinex Instasoothe Sore Throat Relief, Sore Throat Lozenges, Sore Throat Medicine with Hexylresorcinol, Cough Drops Alternative, 40 Elderberry & Wild Cherry Medicated Numbing Throat Drops

Vicks DayQuil & NyQuil SEVERE Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, and Cough, Co-Pack, 2 x 12 OZ

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